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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNKS2
All Species:
18.79
Human Site:
Y376
Identified Species:
34.44
UniProt:
Q9H2K2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2K2
NP_079511.1
1166
126918
Y376
H
C
A
A
A
S
P
Y
P
K
R
K
Q
I
C
Chimpanzee
Pan troglodytes
XP_001137443
1327
142033
H534
H
C
A
V
A
S
L
H
P
K
R
K
Q
V
T
Rhesus Macaque
Macaca mulatta
XP_001090358
1327
142132
H534
H
C
A
V
A
S
L
H
P
K
R
K
Q
V
T
Dog
Lupus familis
XP_534962
1316
141794
Y526
H
C
A
A
A
S
P
Y
P
K
R
K
Q
I
C
Cat
Felis silvestris
Mouse
Mus musculus
NP_001157107
1166
126725
Y376
H
C
A
A
A
S
P
Y
P
K
R
K
Q
I
C
Rat
Rattus norvegicus
NP_001101077
1166
126761
Y376
H
C
A
A
A
S
P
Y
P
K
R
K
Q
I
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508887
1320
142724
H527
H
C
A
V
A
S
L
H
P
K
R
K
Q
V
T
Chicken
Gallus gallus
Q5F478
990
107379
T283
L
H
F
A
A
A
S
T
H
G
A
L
C
L
E
Frog
Xenopus laevis
NP_001088420
1303
140252
H510
H
C
A
V
A
S
L
H
P
K
R
K
Q
I
T
Zebra Danio
Brachydanio rerio
Q502K3
1071
114412
R318
H
M
A
A
I
H
G
R
F
T
R
S
Q
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651410
1181
127927
D375
H
L
A
V
V
S
P
D
G
K
R
K
Q
L
M
Honey Bee
Apis mellifera
XP_396483
1166
127309
Y374
H
C
A
V
A
S
P
Y
P
K
R
K
Q
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186587
1157
126547
F376
H
C
A
S
G
S
A
F
P
K
R
R
Q
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.5
72.5
87.9
N.A.
97.2
97.2
N.A.
72.5
24
73.1
23.3
N.A.
65.3
70.6
N.A.
69.5
Protein Similarity:
100
80.3
80.3
88.2
N.A.
98.8
99
N.A.
80.5
40.3
81.3
38.9
N.A.
79.8
83
N.A.
83.1
P-Site Identity:
100
66.6
66.6
100
N.A.
100
100
N.A.
66.6
13.3
73.3
40
N.A.
53.3
80
N.A.
53.3
P-Site Similarity:
100
80
80
100
N.A.
100
100
N.A.
80
26.6
80
40
N.A.
60
86.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
93
47
77
8
8
0
0
0
8
0
0
0
0
% A
% Cys:
0
77
0
0
0
0
0
0
0
0
0
0
8
0
31
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
0
8
8
0
0
0
0
0
% G
% His:
93
8
0
0
0
8
0
31
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
47
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
85
0
77
0
0
0
% K
% Leu:
8
8
0
0
0
0
31
0
0
0
0
8
0
16
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
47
0
77
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
93
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
93
8
0
0
0
% R
% Ser:
0
0
0
8
0
85
8
0
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
31
% T
% Val:
0
0
0
47
8
0
0
0
0
0
0
0
0
39
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _